Context: Right-clicking on an R-group definition label.

Ungroup: The R-group definition list in question is deceased, but its elements will remain on the canvas.

Duplicate: Takes a copy from the R-group definition in context.

Atom Properties: opens the Atom properties dialog window.

Bond properties: opens the Bond properties dialog window which contains bond types and query properties.

Absolute stereo (chiral)*: Sets the "Absolute" chiral flag on every structure on the canvas, indicating that the molecule(s) represent(s) a single, well-defined stereoisomer.

Context: There is an R-group definition on the canvas and a structure is selected. (This structure can be a part of the definition or another molecule on the canvas.)

Right-click on the label of the R-group definition.

Add to this group: The selected molecules are appended to this particular R-group definition.

Remove from this group: The selected fragments are removed from the R-group definition in question.

Absolute stereo (chiral)*: Sets the "Absolute" chiral flag on every structure on the canvas, indicating that the molecule(s) represent(s) a single, well-defined stereoisomer.

*Absolute stereo flag is displayed only when the chiral flag visibility is turned on in View Settings dialog.