Context: There is an active selection on the canvas. (This structure can be atom, bond, group, etc.) Right-clicking on the selected structure.

Duplicate: Makes a duplicate from the selected structure.

+ R-group attachment: gives an R-group attachment to the atom

- R-group attachment: removes an R-group attachment from the atom

Atom properties: Opens the Atom properties dialog window, where the properties of all the selected atoms can be changed.

Bond properties: Opens the Bond properties dialog window, where the properties of all the selected bonds can be changed.

Mirror horizontally: Mirrors a selected molecule or fragment horizontally.

Mirror vertically: Mirrors a selected molecule or fragment vertically.

Absolute stereo (chiral)*: Sets the "Absolute" chiral flag on the entire structure, indicating that the molecule represents a single, well-defined stereoisomer.

*Absolute stereo flag is displayed only when the chiral flag visibility is turned on in View Settings dialog.