Registering exact matches

Exact matches are automatically registered under the existing parent. All these cases require that the "RegisterNewLots" and "RegisterNewVersions" system switchers are set TRUE for the used source. Exact parent matches can be registered under an existing version in which case specified PCN and CN is not considered, or it can be registered under a new version with a specified CN (if there is one).

E.g. when registering 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetate with 1xNa+ as salt, and diclofenac is already present in the DB, a new version will be created and the preparation (lot) will be moved under it ( figure Autoreg 9 ).

Figure Autoreg 9. Tree with two versions

Registering non-exact matches

In case of a parent match that is not exact (e.g. 2D and/or tautomer), the submission can be successfully autoregistered or it will fall into the staging area, depending on how the actual system switchers are set for the given source.

The system switchers that are involved in the registration of the non-exact matches are: "Register New Lots", "Register New Versions", "Register 2D Parent Matches", "Register Tautomer Parent Matches", "Register 2D-Tautomer Parent Matches", "Register restricted matches" and "Register dictionary CST".

In case of autoregistration no match list and therefore no match action (accept/replace parent matches) is available. The compound to be registered can go under an existing version or it can be registered under a new version

When the compound to be registered has specified PCN and/or CN

The compound to be registered can go under an existing version, in which case specified PCN and/or CN are not considered, or it can be registered under a new version, in which case specified CN, if there is one, is kept.

Autoregistering 2D matches

Autoregistering 2D matches can be allowed if the "Register 2D Parent Matches" system switcher is set TRUE for the used source. In this case the record will be registered under a new PCN and CN.

Autoregistering tautomer matches

Autoregisteing tautomer matches can be allowed if the "Register Tautomer Parent Matches" system switcher is set TRUE for the used source. In this case the record will be registered under a new PCN and CN. If the system switcher is set FALSE, the submission will fall to the Staging area with "ParentTautomeMatch" status message.

Autoregistering 2D&tautomer matches

Autoregisteing 2D&tautomer matches can be allowed if the "Register 2D&Tautomer Parent Matches" system switcher is set TRUE for the used source. In this case the record will be registered under a new PCN and CN.

Autoregistering new compounds with restricted matches

After a match is found for a newly registered compound, it is also checked if the match is restricted or not. In case of a restricted match the submission falls to the Staging area with "RestrictedMatch" status message (if the "Register if matches are restricted" system switcher is set FALSE for the used Source).

If none of the matches are restricted the record will be registered as a new lot either under an existing version (in case of a matching version), under a new version (if the version doesn't exist, but there is a parent exact match) or under a new parent (if it is a 2D/tautomer match).

Autoregistering with CST Dictionary

If the compound to be registered has an unknown CST (not present yet in the CST Dictionary), it will fall to the Staging area. If the compound to be registered has a CST, which is already present in the CST Dictionary, it will be successfully autoregistered.